Magazin, Moleküle

Wie stabil ist Uthever® NMN?

Regelmäßig stellen uns Kunden die Frage: Wie soll ich Uthever® NMN lagern? Wie stabil ist es bei Zimmertemperatur? Muss ich es im Kühlschrank aufbewahren?

In diesem Beitrag möchten wir auf genau diese Fragen eingehen und Ihnen gleichzeitig zeigen, dass Uthever® NMN mit das stabilste Produkt auf dem Markt ist.

Stabilitätstest – Um die Stabilität zu testen, wurden folgende Bedingungen vorausgesetzt:

1. Verpacktes NMN in doppelwandigen Polyethylen Beuteln.

2. Lagerung bei 40℃ 

3. Lagerung bei 75% Luftfeuchtigkeit

Wir sprechen hier also von einer verhältnismäßig hohen, sommerlichen Temperatur in Deutschland und einer typischen Luftfeuchtigkeit bei Raumluft.

Drei unterschiedliche Chargen von Uthever® NMN wurden unter diesen Bedingungen nach einem Monat, nach zwei Monaten, nach drei Monaten und nach sechs Monaten auf Reinheit und Feuchtigkeit geprüft.

Die Ergebnisse staffeln sich wie folgt:

research on the stability of NMN

Wie Sie sehen können hat Uthever® NMN selbst nach sechs Monaten Lagerung unter verhältnismäßig extremen Bedingungen, im Schnitt gerade einmal 0,1% seiner Reinheit eingebüßt.

Die Lagerung bei Zimmertemperatur ist also absolut unbedenklich.

Verwendete Quellen

Superman und die Vitamin B3-Familie

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Uddin, G. M., Yongson, N., Sinclair, D., & Morris, M. (2015). Effects of High Fat Diet Induced Obesity on Mitochondrial Biogenesis and Function–Impact of Exercise or Nicotinamide Mononucleotide (NMN). The FASEB Journal29(1_supplement), 777-8.

Zhang, H. et al.  (2016). NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice. Science352(6292), 1436-1443.

Hwang, E. S., & Hwang, S. Y. (2018). Cellular NAD⁺ level: a key determinant of mitochondrial quality and health. Annals of Geriatric Medicine and Research21(4), 149-157.

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Irie, J. et al. (2020). Effect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese men. Endocrine journal67(2), 153-160.

 

NR vs. NMN – blaue Pille vs. rote Pille

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Airhart, S. E. et al. (2017). An open-label, non-randomized study of the pharmacokinetics of the nutritional supplement nicotinamide riboside (NR) and its effects on blood NAD+ levels in healthy volunteers. PloS one12(12).

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Grozio, A. et al. (2019). Slc12a8 is a nicotinamide mononucleotide transporter. Nature metabolism1(1), 47-57.

Tarantini, S. et al. (2019). Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice. Redox biology24, 101192.

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Podcast David Sinclair

 

Ist Altern eine Krankheit?

Podcast UIBK

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